Cardiac damage in an adolescent patient with COVID-19: a case report

Abstract

COVID-19 has been found to affect the cardiovascular system leading to myocardial damage.
A study of 41 patients in Wuhan, China, found that 12% of COVID-19 patients experienced
virus-related acute cardiac damage.Subsequent bigger Chinese studies also found acute cardiac
damage in 7.2% to 27.8% of hospitalized patients. As a chronicsequela, this condition may
result in cardiomyopathy. We report acase of an adolescent COVID-19 survivor with dilated
cardiomyopathy with no underlying heart disease. A male patient aged 16 years old was
admitted to our outpatient clinic with the primary symptom of exhaustion and had recovered
frommild to moderate COVID-19 one month prior to the visit. No previous history of heart
disease was documented. Physical examination showed no abnormalities. Laboratory results
revealed substantially elevated NT-proBNP (7705 pg/mL) and D-dimer (1850 ng/mL). ECG
presented normal sinus rhythm with poorR wave progression. Echocardiography revealed all
chamber dilatation, eccentric left ventricular hypertrophy, globalhypokinetic, moderate mitral
regurgitation, and reduced ejection fraction (22%). We diagnosed the patient with new-onset
dilated cardiomyopathy and began treatment with candesartan, bisoprolol, furosemide,
spironolactone, rivaroxaban, and trimetazidine. The recovery was steady at three-month
follow-up visit. The emergence of new-onset cardiomyopathy in this previously healthy
adolescent raisesthepossibility of COVID-19 acting asthe sole cause of myocardial injuryin the
absence of underlying heart disease. To avoid further complications, comprehensive evaluation
and effective therapy should be implemented during hospitalization and post-discharge.
Additional tests such as cardiac magnetic resonance imaging and endomyocardial biopsies
shouldbe performed to support final proof.

DOI : 10.35990/amhs.v1n2.p88-96